Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674535 | 0.78 | ALDH1A1 (0.43) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL10665246 | 0.76 | TSHR (0.33) | TSHRFAAHCES2CA1ALDH1A1 | |
| SCHEMBL10672312 | 0.75 | TSHR (0.49) | TSHRNAAAEPHX1FAAHCA12 | |
| SCHEMBL5184556 | 0.75 | TSHR (0.67) | TSHRNAAAEPHX1DGKAFAAH | |
| SCHEMBL4150098 | 0.75 | TSHR (0.67) | TSHRNAAAEPHX1DGKAFAAH | |
| SCHEMBL31365121 | 0.74 | CES2 (0.60) | TSHRDGKAFAAHCES2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10581327 | 0.73 | TSHR (0.45) | TSHRNAAAEPHX1CA12CA1 | |
| Bromide SCHEMBL5181055 | 0.73 | TSHR (0.44) | TSHRNAAAEPHX1CA12CA1 | |
| Hydrochloric Acid SCHEMBL8190290 | 0.73 | TSHR (0.45) | TSHRNAAAEPHX1CA12CA1 | |
| Hydrochloric Acid SCHEMBL9709576 | 0.73 | TSHR (0.45) | TSHRNAAAEPHX1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748087-A | Plastic laminate of furniture foil and method of making | THE WIGGINS TEAPE GROUP LIMITED (GB) | 1988-05-31 | — | — | US | disclosed |
| EP-0183764-B1 | COATING SUBSTRATES | The Wiggins Teape Group Limited (GB) | 1987-11-19 | — | — | EP | disclosed |
| EP-0183764-A1 | COATING SUBSTRATES. | WIGGINS TEAPE GROUP LTD (GB) | 1986-06-11 | — | — | EP | disclosed |
| WO-1986000084-A1 | COATING SUBSTRATES | THE WIGGINS TEAPE GROUP LIMITED (GB) | 1986-01-03 | — | — | WO | disclosed |