Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8190290

CCCCCCO[Ti+2]OCCCCCC.[Cl-].[Cl-]

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
THRB P10828 2/20 0.44
NAAA Q02083 1/20 0.44
CA1 P00915 5/20 0.43
CA2 P00918 5/20 0.43
CA9 Q16790 5/20 0.43
CA12 O43570 2/20 0.43
RAD52 P43351 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
EPHX1 P07099 1/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
LPAR3 Q9UBY5 4/20 0.39
LPAR2 Q9HBW0 3/20 0.39
LPAR1 Q92633 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10581327 1.00 TSHR (0.45) TSHRTHRBNAAACA1CA2
Hydrochloric Acid SCHEMBL9709576 1.00 TSHR (0.45) TSHRTHRBNAAACA1CA2
Hydrochloric Acid SCHEMBL11127961 0.97 CA1 (0.42) TSHRTHRBNAAACA1CA2
Bromide SCHEMBL5181055 0.94 TSHR (0.44) TSHRTHRBNAAACA1CA2
Hydrochloric Acid SCHEMBL234590 0.88 ADRB2 (0.43) TSHRTHRBNAAACA1CA2
SCHEMBL31137801 0.85 ADRB2 (0.45) TSHRTHRBNAAACA1CA2
Iodide SCHEMBL9485433 0.82 ADRB2 (0.43) TSHRTHRBNAAACA1CA2
Bromide SCHEMBL7110716 0.82 ADRB2 (0.43) TSHRTHRBNAAACA1CA2
SCHEMBL11052429 0.82 ADRB2 (0.43) TSHRTHRBNAAACA1CA2
Hydrochloric Acid SCHEMBL234587 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6022628-A BLEND OF BUTYLENE-PROPYLENE COPOLYMER AND SILICA UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-02-08 US disclosed
US-5968865-A COORDINATION CATALYST COMPRISING MAGNESIUM, TITANIUM, HALIDE, AND 1,2-DIALKOXYBENZENE COMPOUNDS; OLEFIN POLYMERIZATION CATALYSTS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-10-19 US disclosed
EP-0739381-B1 POLYMER COMPOSITIONS UNION CARBIDE CHEM PLASTIC (US) 1999-06-16 EP disclosed
EP-0730623-B1 RANDOM COPOLYMER COMPOSITIONS UNION CARBIDE CHEM PLASTIC (US) 1998-03-04 EP disclosed
EP-0398439-B1 Solid alpha-olefin polymerization catalyst components MONTELL TECHNOLOGY COMPANY BV (NL) 1997-04-09 EP disclosed
EP-0470171-B1 POLYMERIZATION PROCESS AND CATALYST SHELL OIL CO (US) 1996-12-04 EP disclosed
EP-0739381-A1 POLYMER COMPOSITIONS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-10-30 EP disclosed
EP-0500530-B1 CATALYST COMPONENT FOR MAKING PRIMARILY ISOTACTIC ELASTOMERIC POLYPROPYLENE OR POLYBUTENE SHELL OIL CO (US) 1996-09-11 EP disclosed
EP-0730623-A1 RANDOM COPOLYMER COMPOSITIONS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-09-11 EP disclosed
EP-0667875-A1 PROCESS FOR POLYMERIZING ALPHA-OLEFIN SHELL OIL COMPANY (US) 1995-08-23 EP disclosed
US-4657995-A STEREOSPECIFIC COORDINATION CATALYST INCLUDING AN ACYL HALIDE SHELL OIL COMPANY (US) 1987-04-14 US disclosed
EP-0216402-A2 Preparation of spherical magnesium alkoxide particles SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-04-01 EP disclosed
US-4548915-A ABSORPTION OF MINERAL OIL INTO CATALYST PORES-STORAGE STABILITY SHELL OIL COMPANY (US) 1985-10-22 US disclosed
US-4535068-A HALOGENATING 4 MAGNESIUM COMPOUND WITH TITANIUM HALIDE;CONTACTING WITH ACID HALIDE SHELL OIL COMPANY (US) 1985-08-13 US disclosed
EP-0135973-A2 Olefin polymerization catalyst components and polymerization process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-04-03 EP disclosed
US-4497905-A HALOGENATED MAGNESIUM ALKOXIDE COMPOUND, TITANIUM, ALUMINUM AND THIONYL CHLORIDE COMPONENTS SHELL OIL COMPANY (US) 1985-02-05 US disclosed
US-4414132-A Olefin polymerization catalyst compositions and a process for the polymerization of olefins employing such compositions SHELL OIL COMPANY (US) 1983-11-08 US disclosed
EP-0019330-B1 OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND A PROCESS FOR THE POLYMERIZATION OF OLEFINS EMPLOYING SUCH COMPOSITIONS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-08-31 EP disclosed
US-4400302-A TITANIUM HALIDE, ALKYL MAGNESIUM SHELL OIL COMPANY (US) 1983-08-23 US disclosed
EP-0019330-A1 Olefin polymerization catalyst compositions and a process for the polymerization of olefins employing such compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1980-11-26 EP disclosed