Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | USP5 | P45974 | 1/20 | 0.45 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12589742 | 0.84 | ALDH1A1 (0.50) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL17116879 | 0.84 | PDE4A (0.56) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8297463 | 0.82 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL10672237 | 0.82 | SMN1; SMN2 (0.55) | KMT2AALDH1A1POLBCYP3A4CYP2D6 | |
| SCHEMBL326869 | 0.82 | NR4A1 (0.65) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16198288 | 0.81 | ALDH1A1 (0.51) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| Hydrochloric Acid SCHEMBL6947520 | 0.81 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL1839310 | 0.81 | PDE4A (0.47) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28186274 | 0.80 | NR4A1 (0.63) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30831804 | 0.80 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734415-A | CARDIOTONIC, HYPOTENSIVE | WARNER-LAMBERT COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| US-4353905-A | CARDIOTONIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1982-10-12 | — | — | US | disclosed |