Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | PDE4A | P27815 | 2/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.58 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADH5 | P11766 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186274 | 0.98 | NR4A1 (0.63) | NR4A1NR4A2ALDH1A1PDE4APDE4B | |
| SCHEMBL30831804 | 0.88 | PDE4A (0.68) | NR4A1NR4A2ALDH1A1PDE4APDE4B | |
| SCHEMBL28100871 | 0.86 | ALDH1A1 (0.58) | NR4A1NR4A2ALDH1A1PDE4APDE4B | |
| SCHEMBL31589965 | 0.86 | NR4A1 (0.64) | NR4A1NR4A2ALDH1A1PDE4APDE4B | |
| SCHEMBL10201831 | 0.85 | RXRA (0.57) | NR4A1NR4A2CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL30558759 | 0.83 | ALDH1A1 (0.71) | NR4A1NR4A2ALDH1A1PDE4APDE4B | |
| SCHEMBL28427931 | 0.83 | NR4A1 (0.47) | NR4A1NR4A2ALDH1A1PDE4APDE4B | |
| SCHEMBL10476781 | 0.82 | NR4A1 (0.60) | NR4A1NR4A2ALDH1A1PDE4APDE4B | |
| SCHEMBL327622 | 0.82 | PDE4A (0.54) | NR4A1NR4A2ALDH1A1PDE4APDE4B | |
| SCHEMBL17116879 | 0.82 | PDE4A (0.56) | NR4A1NR4A2ALDH1A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112090403-B | MAF-stu-13 material with ultra-microporous dia-a network topology structure and synthesis and application thereof | 汕头大学 | 2023-05-30 | — | — | CN | claimed |
| CN-107286099-B | Zinc complex constructed based on 4- (2-methylimidazole) benzoic acid and application thereof | 陕西理工学院 | 2020-09-25 | — | — | CN | claimed |
| CN-107286099-A | Zn complex and its application that one kind is constructed based on 4 (2 methylimidazole) benzoic acid | 陕西理工学院 | 2017-10-24 | — | — | CN | claimed |
| EP-0169164-B1 | IMIDAZOLONECARBONYLARYLIMIDAZOLES; METHOD OF MANUFACTURE, METHOD OF USE AND COMPOSITIONS USEFUL THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-01-31 | — | — | EP | claimed |
| CN-112090403-B | MAF-stu-13 material with ultra-microporous dia-a network topology structure and synthesis and application thereof | 汕头大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-112090403-A | MAF-stu-13 material with ultramicropore dia-a network topological structure and synthesis and application thereof | 汕头大学 | 2020-12-18 | — | — | CN | disclosed |
| CN-107286099-B | Zinc complex constructed based on 4- (2-methylimidazole) benzoic acid and application thereof | 陕西理工学院 | 2020-09-25 | — | — | CN | disclosed |
| CN-107286099-B | Zinc complex constructed based on 4- (2-methylimidazole) benzoic acid and application thereof | 陕西理工学院 | 2020-09-25 | — | — | CN | disclosed |
| CN-107286099-B | Zinc complex constructed based on 4- (2-methylimidazole) benzoic acid and application thereof | 陕西理工学院 | 2020-09-25 | — | — | CN | disclosed |
| EP-2892888-B1 | N-CYCLOPROPYL-N-PIPERIDINYL-AMIDES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |
| EP-2892888-B1 | N-CYCLOPROPYL-N-PIPERIDINYL-AMIDES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |
| CN-107286099-A | Zn complex and its application that one kind is constructed based on 4 (2 methylimidazole) benzoic acid | 陕西理工学院 | 2017-10-24 | — | — | CN | disclosed |
| US-5223623-A | 2-substituted-1(4)-aryl piperazines and the process for their preparation | SCHERING AG (DE) | 1993-06-29 | — | — | US | disclosed |
| EP-0491709-A1 | 2-SUBSTITUTED-1(4)-ARYL PIPERAZINES AND THE PROCESS FOR THEIR PREPARATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | disclosed |
| US-5051422-A | 2-substituted-1(4)-aryl piperazines and the process for their preparation | SCHERING AG (DE) | 1991-09-24 | — | — | US | disclosed |
| WO-1991004250-A1 | 2-SUBSTITUTED-1(4)-ARYL PIPERAZINES AND THE PROCESS FOR THEIR PREPARATION | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-04-04 | — | — | WO | disclosed |
| EP-0169164-B1 | IMIDAZOLONECARBONYLARYLIMIDAZOLES; METHOD OF MANUFACTURE, METHOD OF USE AND COMPOSITIONS USEFUL THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-01-31 | — | — | EP | disclosed |
| US-4709043-A | Process for the preparation of imidazolonecarbonylarylimidazoles | SCHERING A.G. (DE) | 1987-11-24 | — | — | US | disclosed |
| EP-0169164-A1 | Imidazolonecarbonylarylimidazoles; method of manufacture, method of use and compositions useful thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-01-22 | — | — | EP | disclosed |
| US-4556665-A | Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones | SCHERING A.G. (DE) | 1985-12-03 | — | — | US | disclosed |