SCHEMBL10670321

SCHEMBL10670321

CCC(CC)C(=O)[O-].CCC(CC)C(=O)[O-].[Ni+2]

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.58
TSHR P16473 3/20 0.57
CYP3A4 P08684 2/20 0.57
NFKB1 P19838 2/20 0.57
NPSR1 Q6W5P4 2/20 0.57
USP2 O75604 1/20 0.42
MAPK1 P28482 1/20 0.39
CA1 P00915 3/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37
FFAR3 O14843 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1506862 0.94 CA2 (0.58) CA2TSHRCYP3A4NFKB1NPSR1
SCHEMBL1030692 0.94 CA2 (0.58) CA2TSHRCYP3A4NFKB1NPSR1
Zinc Ion SCHEMBL2355344 0.94 CA2 (0.58) CA2TSHRCYP3A4NFKB1NPSR1
SCHEMBL17178412 0.94 CA2 (0.58) CA2TSHRCYP3A4NFKB1NPSR1
SCHEMBL98742 0.94 CA2 (0.58) CA2TSHRCYP3A4NFKB1NPSR1
SCHEMBL8574352 0.94 CA2 (0.58) CA2TSHRCYP3A4NFKB1NPSR1
SCHEMBL5079455 0.94 CA2 (0.58) CA2TSHRCYP3A4NFKB1NPSR1
Potassium Ion SCHEMBL267337 0.94
SCHEMBL3343198 0.94 CA2 (0.58) CA2TSHRCYP3A4NFKB1NPSR1
SCHEMBL8747771 0.94 CA2 (0.58) CA2TSHRCYP3A4NFKB1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4755546-A Stabilized olefin polymers BORG-WARNER CHEMICALS, INC. (US) 1988-07-05 US disclosed
US-4668722-A Hindered piperidinoalcohol 1,1,1-trioxyalkane stabilizers MACK GERRY P 1987-05-26 US disclosed
US-4501838-A WITH ESTER OF PENTAERYTHRITOL MONOACETATE BORG-WARNER CHEMICALS, INC. (US) 1985-02-26 US disclosed
US-4321191-A THIO-CONTAINING POLYESTERS, POLYCARBONATES, AND COMPOUNDS; HEAT RESISTANCE; DISCOLORATION INHIBITION; MECHANICAL PROPERTIES ARGUS CHEMICAL CORP. (US) 1982-03-23 US disclosed
US-4298520-A PHOSPHITES OR PHOSPHATES ARGUS CHEMICAL CORP. (US) 1981-11-03 US disclosed
US-4293472-A O-ALKYLHYDROXYBENZYLPROPANE-1,3-DIOL ESTERS CONTAINING SULFIDE GROUPS ADEKA ARGUS CHEMICAL CO., LTD. 1981-10-06 US disclosed
US-4257927-A Inorganic organic coester stabilizers ARGUS CHEMICAL CORP. (US) 1981-03-24 US disclosed
US-4255301-A HEAT RESISTANCE, PHOTOSTABILITY ARGUS CHEMICAL CORPORATION (US) 1981-03-10 US disclosed
US-4233414-A FOR SYNTHETIC RESINS HEAT RESISTANCE ARGUS CHEMICAL CORPORATION (US) 1980-11-11 US disclosed
US-4225474-A Organophosphonate coester stabilizers ARGUS CHEMICAL CORP. (US) 1980-09-30 US disclosed
EP-0006842-A1 Organophosphonate co-ester, stabiliser composition containing it and synthetic resin stabilised therewith S.A. Diamond Shamrock Benelux N.V. (BE) 1980-01-23 EP disclosed
EP-0006091-A1 2-Hydroxy-4-alkoxy-5-aminomethylbenzophenones and their use as photostabilisers in polymeric compositions, a process for preparing a 5,5-methylene bis (2-hydroxy-4-alkoxybenzophenone). S.A. Diamond Shamrock Benelux N.V. (BE) 1980-01-09 EP disclosed
US-4174297-A Polyhydric phenol coester stabilizers ARGUS CHEMICAL CORPORATION (US) 1979-11-13 US disclosed
US-4171298-A SUBSTITUTED ORTHO-ALKYLHYDROXYBENZYLPROPANE-1,3-DIOL ESTERS ARGUS CHEMICAL CORPORATION (US) 1979-10-16 US disclosed
US-4169089-A PHOTOSTABILIZERS FOR POLYMERS ARGUS CHEMICAL CORPORATION (US) 1979-09-25 US disclosed
US-4146517-A FOR SYNTHETIC RESINS AGAINST HEAT ARGUS CHEMICAL CORPORATION (US) 1979-03-27 US disclosed
US-4124564-A LIGHT AND HEAT RESISTANCE ARGUS CHEMICAL CORPORATION (US) 1978-11-07 US disclosed
US-4107136-A Synthetic resin stabilizer comprising an organic phosphite and a carbonate ARGUS CHEMICAL CORPORATION (US) 1978-08-15 US disclosed
US-4105629-A SYNTHETIC RESIN STABILIZER COMPRISING A THIOETHER ESTER AND HINDERED PHENOLIC CARBONATE ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4104217-A OF POLYHYDRIC PHENOLS ARGUS CHEMICAL CORPORATION (US) 1978-08-01 US disclosed