Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335552 | 0.84 | CYP1A2 (0.56) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL11493115 | 0.84 | TSPO (0.50) | TSPOMEN1KMT2ARAD52POLB | |
| SCHEMBL29773622 | 0.78 | MAPT (0.65) | TSPOMEN1KMT2ARAD52POLB | |
| SCHEMBL871044 | 0.78 | MAPT (0.65) | TSPOMEN1KMT2ARAD52POLB | |
| SCHEMBL29696470 | 0.77 | MAOA (0.53) | TSPOMEN1KMT2ARAD52 | |
| SCHEMBL2456180 | 0.76 | POLB (0.53) | TSPOMEN1KMT2APOLBMAPT | |
| SCHEMBL10954372 | 0.75 | TSPO (0.51) | TSPOMEN1KMT2ARAD52MAPT | |
| SCHEMBL17955864 | 0.75 | MAPT (0.58) | TSPOMEN1KMT2ARAD52POLB | |
| SCHEMBL2246814 | 0.75 | CYP19A1 (0.70) | TSPOMEN1KMT2ARAD52MAPT | |
| SCHEMBL1921157 | 0.75 | ALDH1A1 (0.60) | TSPOMEN1KMT2ARAD52POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743659-A | Chemical modification of polydiacetylene crystals | GTE LABORATORIES INCORPORATED (US) | 1988-05-10 | — | — | US | disclosed |
| US-4681920-A | Chemical modification of polydiacetylene crystals | GTE LABORATORIES INCORPORATED (US) | 1987-07-21 | — | — | US | disclosed |
| US-4208501-A | PHOTOCONDUCTORS AND OPTICAL DEVICES | ALLIED CHEMICAL CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4125534-A | HIGH ENERGY RADIATION DOSAGE INDICATORS | ALLIED CHEMICAL CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |