Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29750678 | 0.83 | NPC1 (0.51) | SLC6A3TGFBR1P2RX3GSTP1GSTM2 | |
| SCHEMBL24199697 | 0.81 | TDP1 (0.57) | TDP1SMN1; SMN2RAB9A | |
| SCHEMBL2436089 | 0.78 | P2RX3 (0.41) | SLC6A3TGFBR1P2RX3GSTP1GSTM2 | |
| SCHEMBL4082004 | 0.77 | GSTP1 (0.49) | SLC6A3TGFBR1P2RX3GSTP1GSTM2 | |
| SCHEMBL30423559 | 0.76 | P2RX7 (0.50) | TGFBR1P2RX3GSTP1GSTM2CCNA2 | |
| SCHEMBL10671807 | 0.76 | P2RX3 (0.40) | SLC6A3TGFBR1P2RX3GSTP1GSTM2 | |
| SCHEMBL29633838 | 0.73 | SLC6A3 (0.38) | SLC6A3TGFBR1P2RX3GSTP1GSTM2 | |
| SCHEMBL28741551 | 0.73 | P2RX3 (0.39) | SLC6A3TGFBR1P2RX3GSTP1GSTM2 | |
| SCHEMBL6918851 | 0.71 | GSTP1 (0.46) | SLC6A3TGFBR1P2RX3GSTP1GSTM2 | |
| SCHEMBL2407455 | 0.71 | GSTP1 (0.46) | SLC6A3TGFBR1P2RX3GSTP1GSTM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757078-A | Antiinflammatory agents, psoriasis | E. R. SQUIBB & SONS, INC. (US) | 1988-07-12 | — | — | US | disclosed |