Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499823 | 0.74 | TAAR1 (0.50) | CYP2D6KDM4EKMT2ATYRTAAR1 | |
| SCHEMBL169730 | 0.74 | TAAR1 (0.50) | CYP2D6KDM4EKMT2ATYRTAAR1 | |
| Isopropylbenzene SCHEMBL2638430 | 0.72 | CYP2D6 (0.48) | CYP2D6CYP1A2CYP3A4CYP2C9KCNA5 | |
| Methane SCHEMBL11277700 | 0.72 | KMT2A (0.50) | CYP2D6KDM4EKMT2ATYRTAAR1 | |
| Hydrogen Peroxide SCHEMBL8846644 | 0.72 | ESR1 (0.55) | CYP2D6CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL3900499 | 0.72 | TAAR1 (0.48) | CYP2D6KDM4EKMT2ATYRTAAR1 | |
| Ethane SCHEMBL11274743 | 0.72 | TAAR1 (0.48) | CYP2D6KDM4EKMT2ATYRTAAR1 | |
| SCHEMBL8643448 | 0.72 | ESR1 (0.55) | CYP2D6KDM4EKMT2ATYRTAAR1 | |
| Bromide SCHEMBL2016300 | 0.72 | TAAR1 (0.48) | CYP2D6KDM4EKMT2ATYRTAAR1 | |
| Ammonia Solution, Strong SCHEMBL6989331 | 0.72 | TAAR1 (0.48) | CYP2D6KDM4EKMT2ATYRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101195711-B | Polyamic acid composition and alignment film prepared from same | DALI POLYMER CO LTD | 2012-07-04 | — | — | CN | claimed |
| CN-101195711-B | Polyamic acid composition and alignment film prepared from same | DALI POLYMER CO LTD | 2012-07-04 | — | — | CN | disclosed |
| US-4721712-A | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents | PFIZER INC. (US) | 1988-01-26 | — | — | US | disclosed |
| US-4658037-A | RHEUMATIC DISEASES | PFIZER INC. (US) | 1987-04-14 | — | — | US | disclosed |