Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | TOP1 | P11387 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21580248 | 0.98 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG | |
| Hydrochloric Acid SCHEMBL9575644 | 0.88 | FAAH (0.47) | FAAHTRPV1TERTPTPN1PPARG | |
| Hydrochloric Acid SCHEMBL28769371 | 0.88 | FAAH (0.47) | FAAHTRPV1TERTPTPN1PPARG | |
| Hydrochloric Acid SCHEMBL4893513 | 0.87 | SLC22A1 (0.52) | HSD17B10ALOX15TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL721018 | 0.87 | SLC22A1 (0.52) | HSD17B10ALOX15TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL4895225 | 0.87 | SLC22A1 (0.52) | HSD17B10ALOX15TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL9575880 | 0.87 | SLC22A1 (0.52) | HSD17B10ALOX15TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL491727 | 0.87 | SLC22A1 (0.52) | HSD17B10ALOX15TP53CYP3A4 | |
| SCHEMBL9575935 | 0.86 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG | |
| SCHEMBL6551720 | 0.86 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761472-A | Isolation and purification of hemin | BASF AKTIENGESELLSCHAFT (DE) | 1988-08-02 | — | — | US | disclosed |