Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.49 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.49 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213830 | 1.00 | MAPT (0.51) | MAPTLMNAPOLBGLO1GAA | |
| SCHEMBL12211765 | 1.00 | MAPT (0.51) | MAPTLMNAPOLBGLO1GAA | |
| SCHEMBL2897877 | 0.93 | KMT2A (0.57) | MAPTLMNAPOLBGAAMEN1 | |
| SCHEMBL5011134 | 0.89 | ALOX5 (0.58) | MAPTLMNAPOLBGLO1GAA | |
| SCHEMBL9125332 | 0.89 | MEN1 (0.53) | MAPTLMNAPOLBMEN1KMT2A | |
| SCHEMBL9125329 | 0.89 | MEN1 (0.53) | MAPTLMNAPOLBMEN1KMT2A | |
| SCHEMBL10671345 | 0.89 | MEN1 (0.50) | MAPTLMNAPOLBGLO1GAA | |
| SCHEMBL10671337 | 0.89 | MEN1 (0.50) | MAPTLMNAPOLBGLO1GAA | |
| SCHEMBL10376451 | 0.87 | EGFR (0.56) | MAPTLMNAPOLBGLO1GAA | |
| SCHEMBL4573284 | 0.85 | ALOX5 (0.48) | MAPTLMNAPOLBGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4722931-A | MUSCLE RELAXANTS | LABORATORIOS DELAGRANGE (ES) | 1988-02-02 | — | — | US | disclosed |