SCHEMBL2213830

SCHEMBL2213830

CCOC(=O)C(=Cc1cc(OC)c(O)c(OC)c1)C(C)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.51
LMNA P02545 5/20 0.51
POLB P06746 3/20 0.51
GLO1 Q04760 2/20 0.50
GAA P10253 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MEN1 O00255 8/20 0.49
KMT2A Q03164 8/20 0.49
PLIN1 O60240 1/20 0.49
PLIN5 Q00G26 1/20 0.49
ABHD5 Q8WTS1 1/20 0.49
ALDH1A1 P00352 5/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 2/20 0.47
HSP90AA1 P07900 1/20 0.47
NPSR1 Q6W5P4 3/20 0.47
PKM P14618 2/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALOX5 P09917 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12211765 1.00 MAPT (0.51) MAPTLMNAPOLBGLO1GAA
SCHEMBL10673449 1.00 MAPT (0.51) MAPTLMNAPOLBGLO1GAA
SCHEMBL2897877 0.93 KMT2A (0.57) MAPTLMNAPOLBGAAMEN1
SCHEMBL5011134 0.89 ALOX5 (0.58) MAPTLMNAPOLBGLO1GAA
SCHEMBL9125332 0.89 MEN1 (0.53) MAPTLMNAPOLBMEN1KMT2A
SCHEMBL9125329 0.89 MEN1 (0.53) MAPTLMNAPOLBMEN1KMT2A
SCHEMBL10671345 0.89 MEN1 (0.50) MAPTLMNAPOLBGLO1GAA
SCHEMBL10671337 0.89 MEN1 (0.50) MAPTLMNAPOLBGLO1GAA
SCHEMBL10376451 0.87 EGFR (0.56) MAPTLMNAPOLBGLO1GAA
SCHEMBL4573284 0.85 ALOX5 (0.48) MAPTLMNAPOLBGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003082-B2 Photostable organic sunscreen composition MERCK PATENT GMBH (DE) 2011-08-23 US claimed
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2010-02-25 US claimed
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed
WO-2008083974-A1 ACTIVE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2008-07-17 WO claimed
WO-2008067928-A1 UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE ISDIN S.A. (ES) 2008-06-12 WO claimed
US-20070059258-A1 Photostable organic sunscreen composition MERCK PATENT GMBH (DE) 2007-03-15 US claimed
US-7166273-B2 Photo stable organic sunscreen compositions EMD CHEMICALS, INC. (US) 2007-01-23 US claimed
US-7150876-B2 Methods for stabilizing ingredients within cosmetics, personal care and household products MERCK PATENT GMBH (DE) 2006-12-19 US claimed
EP-1406582-B1 PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM MERCK PATENT GMBH (DE) 2006-10-25 EP claimed
US-20050244349-A1 Methods for stabilizing ingredients within cosmetics, personal care and household products SUSONITY Commercial GmbH (DE) 2005-11-03 US claimed
US-20040247536-A1 Photo stable organic sunscreen compositions EMD CHEMICALS, INC. 2004-12-09 US claimed
US-20030108492-A1 PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM EM INDUSTRIES 2003-06-12 US claimed
US-20240122828-A1 ALKENONE-BASED FORMULATIONS FOR TOPICAL APPLICATIONS WESTERN WASHINGTON UNIVERSITY 2024-04-18 US disclosed
WO-2024003594-A1 PERSONAL CARE COMPOSITIONS COMPRISING PANCRATIUM MARITIMUM Galderma Holding SA (CH) 2024-01-04 WO disclosed
US-11839675-B2 Alkenone-based formulations for topical applications WESTERN WASHINGTON UNIVERSITY (US) 2023-12-12 US disclosed
WO-2023192538-A1 PERSONAL CARE COMPOSITIONS FOR SENSITIVE SKIN AND METHODS OF USE Galderma Holding SA (CH) 2023-10-05 WO disclosed
US-6602515-B2 Alpha-acetyl-3,5-dimethoxy-4-hydroxy cinnamate ester; dipalmitoyl-3,5- dimethoxy-4-hydroxy benzylidene malonate or amide derivatives EM INDUSTRIES 2003-08-05 US disclosed
US-20030108492-A1 PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM EM INDUSTRIES 2003-06-12 US disclosed
WO-2003007906-A1 PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM MERCK PATENT GMBH (DE) 2003-01-30 WO disclosed
US-4722931-A MUSCLE RELAXANTS LABORATORIOS DELAGRANGE (ES) 1988-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839675-B2 Alkenone-based formulations for topical applications CUTA, LAGE3, KRT18 MAPT 1549/4885LMNA 447/4885POLB 380/4885
US-20050244349-A1 Methods for stabilizing ingredients within cosmetics, personal care and household products CUTA, TYR, LAGE3 MAPT 328/4885LMNA 1379/4885POLB 325/4885
US-20070059258-A1 Photostable organic sunscreen composition SUN2, ERCC1, PPOX MAPT 105/4885LMNA 3000/4885POLB 508/4885
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION UGT2B17, TACR2, UGT1A1 MAPT 922/4885LMNA 1819/4885POLB 1209/4885
US-20240122828-A1 ALKENONE-BASED FORMULATIONS FOR TOPICAL APPLICATIONS CUTA, LAGE3, DSG1 MAPT 2360/4885LMNA 759/4885POLB 41/4885
US-20030108492-A1 PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM ERCC1, ERCC4, OGG1 MAPT 1118/4885LMNA 1432/4885POLB 642/4885
US-20040247536-A1 Photo stable organic sunscreen compositions SUN2, CCNB1, TYR MAPT 272/4885LMNA 2596/4885POLB 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.