SCHEMBL1067390

SCHEMBL1067390

C=CC(=O)OC(CC)[Si](OCC)(OCC)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.35
THRA P10827 1/20 0.33
GSTO1 P78417 1/20 0.33
ALDH1A1 P00352 2/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 3/20 0.31
MEN1 O00255 2/20 0.31
MAPT P10636 4/20 0.31
PIN1 Q13526 1/20 0.31
MDM4 O15151 1/20 0.30
LMNA P02545 1/20 0.30
MDM2 Q00987 1/20 0.30
AKT1 P31749 1/20 0.30
GAA P10253 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
NPC1 O15118 1/20 0.30
TET3 O43151 1/20 0.30
FBXL19 Q6PCT2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1063251 0.90 THRB (0.37) THRBTHRAALDH1A1CYP3A4CYP2C9
SCHEMBL1068329 0.88 THRB (0.36) THRBTHRAGSTO1ALDH1A1CYP3A4
SCHEMBL8668330 0.86 THRB (0.35) THRBTHRAGSTO1ALDH1A1CYP3A4
SCHEMBL1066828 0.85 THRB (0.36) THRBTHRAGSTO1KMT2AMEN1
SCHEMBL3132567 0.81 MAPT (0.35) THRBALDH1A1KMT2AMEN1MAPT
SCHEMBL8672651 0.80 THRB (0.36) THRBTHRAGSTO1ALDH1A1CYP3A4
SCHEMBL1066663 0.78 ALDH1A1 (0.35) THRBGSTO1ALDH1A1CYP3A4CYP2C9
SCHEMBL9245923 0.77 THRB (0.35) THRBTHRAGSTO1ALDH1A1CYP3A4
SCHEMBL1063226 0.76 THRB (0.41) THRBTHRAALDH1A1CYP3A4CYP2C9
SCHEMBL1067079 0.75 TSHR (0.34) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8829142-B2 Curable composition and process for production of organosilicon compound TOAGOSEI CO., LTD. (JP) 2014-09-09 US disclosed
EP-2270070-B1 CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO LTD (JP) 2014-07-30 EP disclosed
EP-2565217-B1 Curable composition and process for production of organosilicon compound TOAGOSEI CO LTD (JP) 2014-05-14 EP disclosed
US-20130149455-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO., LTD. (JP) 2013-06-13 US disclosed
EP-2565217-A1 Curable composition and process for production of organosilicon compound TOAGOSEI CO., LTD. (JP) 2013-03-06 EP disclosed
US-20110071255-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO., LTD. (JP) 2011-03-24 US disclosed
EP-2270070-A1 CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND Toagosei Co., Ltd (JP) 2011-01-05 EP disclosed
US-5738976-A HEAT RESISTANT, STORAGE STABLE POLYSILSESQUIOXANE MIXED WITH PHOTOSENSITIZER; PHOTORESISTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-04-14 US disclosed