Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674246 | 1.00 | SLC6A4 (0.45) | SLC6A4SLC6A3SIGMAR1SMN1; SMN2TBXA2R | |
| SCHEMBL9061660 | 0.79 | LMNA (0.45) | SLC6A4SLC6A3SIGMAR1SMN1; SMN2TSHR | |
| SCHEMBL9529300 | 0.79 | LMNA (0.45) | SLC6A4SLC6A3SIGMAR1SMN1; SMN2TSHR | |
| SCHEMBL9061654 | 0.79 | LMNA (0.45) | SLC6A4SLC6A3SIGMAR1SMN1; SMN2TSHR | |
| SCHEMBL11161913 | 0.78 | DRD1 (0.38) | DRD2DRD3MAPK1 | |
| SCHEMBL11115905 | 0.77 | DRD2 (0.37) | DRD2DRD3MAPK1 | |
| SCHEMBL10552454 | 0.75 | LMNA (0.46) | SLC6A4SLC6A3SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10552460 | 0.75 | LMNA (0.46) | SLC6A4SLC6A3SIGMAR1SMN1; SMN2ALDH1A1 | |
| Fumaric Acid SCHEMBL30357983 | 0.74 | LMNA (0.46) | SLC6A4SLC6A3SIGMAR1SMN1; SMN2TSHR | |
| SCHEMBL10556593 | 0.73 | ALDH1A1 (0.43) | SLC6A4SMN1; SMN2ALDH1A1TSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269755-A1 | DIBENZ b,e OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |