Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.55 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | NFE2 | Q16621 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677230 | 0.85 | HSD11B1 (0.49) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL14605762 | 0.84 | HSD11B1 (0.59) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL10677887 | 0.82 | HSD11B1 (0.57) | HSD11B1ALDH1A1 | |
| SCHEMBL10672820 | 0.82 | HSD11B1 (0.66) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL10675268 | 0.81 | HSD11B1 (0.53) | HSD11B1ALDH1A1 | |
| SCHEMBL10680871 | 0.81 | HSD11B1 (0.55) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL10677226 | 0.80 | ALDH1A1 (0.62) | ALDH1A1NTRK1NTRK2NFE2POLB | |
| SCHEMBL10674370 | 0.78 | HSD11B1 (0.52) | HSD11B1ALDH1A1 | |
| SCHEMBL10670995 | 0.78 | HSD11B1 (0.64) | HSD11B1PKMHTTNLRP3ALDH1A1 | |
| SCHEMBL10674290 | 0.78 | HSD11B1 (0.57) | HSD11B1PKMHTTNLRP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766120-A | ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| US-4663323-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0035046-B1 | NOVEL TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |
| US-4540703-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0035046-A1 | Novel tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |