Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675268 | 0.97 | HSD11B1 (0.53) | HSD11B1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10676166 | 0.96 | HPGD (0.51) | HSD11B1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10680871 | 0.90 | HSD11B1 (0.55) | HSD11B1SMN1; SMN2DAGLATP53ALDH1A1 | |
| SCHEMBL10681785 | 0.83 | HSD11B1 (0.47) | HSD11B1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4406817 | 0.81 | HSD11B1 (0.54) | HSD11B1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL10670995 | 0.80 | HSD11B1 (0.64) | HSD11B1NPC1RAB9AKMT2ARXFP1 | |
| SCHEMBL10681783 | 0.80 | ALDH1A1 (0.60) | SMN1; SMN2KMT2ATP53ALDH1A1 | |
| SCHEMBL22716411 | 0.80 | HSD11B1 (0.52) | HSD11B1KMT2AALDH1A1 | |
| SCHEMBL4413278 | 0.80 | HSD11B1 (0.52) | HSD11B1KMT2AALDH1A1 | |
| SCHEMBL4407255 | 0.80 | HSD11B1 (0.55) | HSD11B1SMN1; SMN2KMT2AHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766120-A | ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| US-4663323-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4540703-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-09-10 | — | — | US | disclosed |