Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678493 | 0.87 | PTPN11 (0.47) | PTPN11L3MBTL1PDK2MAPTHPGD | |
| SCHEMBL10678962 | 0.81 | RAB9A (0.55) | L3MBTL1MAPTHPGDNPSR1KMT2A | |
| SCHEMBL10678955 | 0.80 | HRH3 (0.60) | L3MBTL1KDM4EKMT2ATSHR | |
| SCHEMBL23812923 | 0.76 | CYP24A1 (0.48) | L3MBTL1MAPTHPGDATMCSNK2A2 | |
| SCHEMBL10679767 | 0.76 | BCHE (0.45) | PTPN11L3MBTL1KDM4E | |
| SCHEMBL10678890 | 0.75 | L3MBTL1 (0.43) | L3MBTL1MAPTHPGDATMKDM4E | |
| SCHEMBL31111406 | 0.75 | L3MBTL1 (0.50) | L3MBTL1MAPTHPGDATMKDM4E | |
| SCHEMBL10674932 | 0.74 | PPARG (0.45) | PTPN11PDK2MAPTHPGDKMT2A | |
| SCHEMBL10679965 | 0.73 | TSHR (0.44) | L3MBTL1KMT2ATSHR | |
| SCHEMBL11022638 | 0.73 | L3MBTL1 (0.44) | L3MBTL1MAPTHPGDATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792570-A | 3- and 4-biphenyloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |