SCHEMBL31111406

SCHEMBL31111406

CCc1cc(OCCCCCl)ccc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.50
PDIA6 Q15084 1/20 0.41
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 2/20 0.40
P4HB P07237 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
TSHR P16473 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
GPR84 Q9NQS5 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13652565 0.88 CA12 (0.47) L3MBTL1KDM4EALDH1A1THRATHRB
SCHEMBL2133555 0.85 L3MBTL1 (0.44) L3MBTL1PDIA6KDM4EALDH1A1THRA
SCHEMBL22483601 0.84 CA12 (0.47) L3MBTL1KDM4EALDH1A1CA12CA1
SCHEMBL2136395 0.81 L3MBTL1 (0.62) L3MBTL1KDM4EALDH1A1P4HBNPSR1
SCHEMBL2721920 0.78 L3MBTL1 (0.49) L3MBTL1KDM4EALDH1A1P4HBNPSR1
SCHEMBL2133616 0.76 BRD4 (0.55) MAPTSMN1; SMN2
SCHEMBL2278511 0.76 KDM4E (0.41) L3MBTL1PDIA6KDM4EALDH1A1THRA
SCHEMBL31111369 0.75 PDIA6 (0.40) L3MBTL1PDIA6ALDH1A1THRATHRB
SCHEMBL10677136 0.75 PTPN11 (0.48) L3MBTL1KDM4EP4HBNPSR1TSHR
SCHEMBL2721919 0.75 KDM4E (0.52) KDM4EALDH1A1P4HBNPSR1THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673424-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS Regeneron Pharmaceuticals, Inc. (US) 2026-01-07 EP disclosed
WO-2024182268-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS REGENERON PHARMACEUTICALS, INC. (US) 2024-09-06 WO disclosed