Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150382 | 0.89 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TDP1RAB9APOLB | |
| SCHEMBL9150388 | 0.87 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TDP1RAB9APOLB | |
| SCHEMBL9150392 | 0.87 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TDP1RAB9APOLB | |
| SCHEMBL16065419 | 0.86 | L3MBTL1 (0.58) | ALDH1A1L3MBTL1TDP1RAB9AGAA | |
| SCHEMBL10676002 | 0.80 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1TDP1RAB9APOLB | |
| SCHEMBL10679958 | 0.78 | ALDH1A1 (0.36) | ALDH1A1RAB9APOLBHTTKMT2A | |
| SCHEMBL10671733 | 0.78 | ALDH1A1 (0.39) | ALDH1A1RAB9APOLBSMN1; SMN2NPC1 | |
| SCHEMBL10683583 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1L3MBTL1TDP1RAB9APOLB | |
| SCHEMBL27672224 | 0.78 | ALDH1A1 (0.36) | ALDH1A1POLBGAAHTTKMT2A | |
| SCHEMBL16065420 | 0.76 | L3MBTL1 (0.58) | ALDH1A1L3MBTL1TDP1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789675-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-06 | — | — | US | disclosed |
| EP-0233728-A1 | 1,4-Benzoxazine derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-08-26 | — | — | EP | disclosed |