Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150388 | 0.91 | ALDH1A1 (0.47) | ALDH1A1LMNAGAAHPGDL3MBTL1 | |
| SCHEMBL9150392 | 0.91 | ALDH1A1 (0.47) | ALDH1A1LMNAGAAHPGDL3MBTL1 | |
| SCHEMBL10677188 | 0.89 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDL3MBTL1TDP1 | |
| SCHEMBL16065419 | 0.78 | L3MBTL1 (0.58) | ALDH1A1LMNAGAAHPGDL3MBTL1 | |
| SCHEMBL17055832 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAGAAHPGDPOLB | |
| SCHEMBL16065420 | 0.75 | L3MBTL1 (0.58) | ALDH1A1LMNAGAAHPGDL3MBTL1 | |
| SCHEMBL4825004 | 0.75 | L3MBTL1 (0.58) | ALDH1A1LMNAGAAHPGDL3MBTL1 | |
| SCHEMBL6256322 | 0.75 | GAA (0.52) | ALDH1A1LMNAGAAHPGDL3MBTL1 | |
| SCHEMBL28258113 | 0.74 | ALDH1A1 (0.56) | ALDH1A1GAAHPGDL3MBTL1TDP1 | |
| SCHEMBL27890906 | 0.74 | LMNA (0.56) | ALDH1A1LMNAGAAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5474988-A | Analgesics, antiinflammatory agents | KALI-CHEMIE PHARMA GMBH (DE) | 1995-12-12 | — | — | US | disclosed |
| EP-0614899-A1 | 5-Phenyl-pyrrolo-1,4-benzoxazine and thiazine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1994-09-14 | — | — | EP | disclosed |