SCHEMBL1067751

SCHEMBL1067751

FC(F)Oc1[c]cccc1C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.36
TRPA1 O75762 1/20 0.33
ULK1 O75385 1/20 0.31
IDO1 P14902 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22729269 0.84 TRPA1 (0.35) TRPA1IDO1
SCHEMBL1068440 0.77 HSD11B1 (0.33) SLC22A12TRPA1IDO1
SCHEMBL162258 0.77 KMT2A (0.33) IDO1
SCHEMBL1063855 0.75 KCNK3 (0.30)
SCHEMBL899973 0.75 DRD1 (0.35)
SCHEMBL900828 0.75 KMT2A (0.33)
SCHEMBL1081977 0.73
SCHEMBL1066629 0.73
SCHEMBL1067050 0.73
SCHEMBL900699 0.73 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3167716-A1 SUBSTITUTED OXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2017-05-17 EP disclosed
WO-2011006886-A2 AZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT XIV BASF SE (DE) 2011-01-20 WO disclosed
WO-2010149758-A1 ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES BASF SE (DE) 2010-12-29 WO disclosed