Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673176 | 0.77 | ALDH1A1 (0.52) | ALDH1A1EPHX1 | |
| SCHEMBL1672558 | 0.76 | ALDH1A1 (0.50) | ALDH1A1EPHX1 | |
| SCHEMBL1064167 | 0.75 | — | — | |
| SCHEMBL6073178 | 0.74 | ALDH1A1 (0.42) | ALDH1A1EPHX1 | |
| SCHEMBL14779338 | 0.73 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL14297001 | 0.73 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL4555813 | 0.72 | ALDH1A1 (0.41) | ALDH1A1EPHX1 | |
| SCHEMBL8671796 | 0.72 | SHBG (0.41) | ALDH1A1EPHX1 | |
| SCHEMBL3380518 | 0.72 | ALDH1A1 (0.41) | ALDH1A1EPHX1 | |
| SCHEMBL2586909 | 0.71 | SHBG (0.45) | ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274297-A1 | PYRROLIDINONE GLUCOKINASE ACTIVATORS | F. Hoffmann-La Roche AG (CH) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009127546-A1 | PYRROLIDINONE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-10-22 | — | — | WO | disclosed |