SCHEMBL9673176

SCHEMBL9673176

CC(OS(C)(=O)=O)C1CCCC1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
EPHX1 P07099 1/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31
SHBG P04278 1/20 0.31
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ARNT P27540 1/20 0.30
EPAS1 Q99814 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1672558 0.98 ALDH1A1 (0.50) ALDH1A1EPHX1CA12CA1CA7
SCHEMBL14779338 0.95 ALDH1A1 (0.52) ALDH1A1ADH1BADH1CADH1AARNT
SCHEMBL14297001 0.95 ALDH1A1 (0.52) ALDH1A1ADH1BADH1CADH1AARNT
SCHEMBL14777975 0.90 ALDH1A1 (0.57) ALDH1A1CA1
SCHEMBL1373078 0.80 ALDH1A1 (0.46) ALDH1A1
SCHEMBL470596 0.80 ALDH1A1 (0.46) ALDH1A1
SCHEMBL30962982 0.80 ALDH1A1 (0.46) ALDH1A1
SCHEMBL7023606 0.78 ALDH1A1 (0.36) ALDH1A1EPHX1ADH1BADH1CADH1A
SCHEMBL14779295 0.77 SHBG (0.38) ALDH1A1EPHX1SHBG
SCHEMBL6073178 0.77 ALDH1A1 (0.42) ALDH1A1EPHX1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0232912-B1 HYDROXAMIC ACIDS OF 7-OXABICYCLOHEPTANE SUBSTITUTED ETHERS E.R. Squibb & Sons, Inc. (US) 1992-05-13 EP disclosed
EP-0161904-B1 TETRAHYDROFURANYL AND TETRAHYDROTHIENYL SUBSTITUTED ETHERS E.R. Squibb & Sons, Inc. (US) 1989-10-18 EP disclosed
EP-0232912-A1 Hydroxamic acids of 7-oxabicycloheptane substituted ethers E.R. Squibb & Sons, Inc. (US) 1987-08-19 EP disclosed
US-4654366-A ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPSORIATIC E. R. SQUIBB & SONS, INC. (US) 1987-03-31 US disclosed
US-4647585-A Bicycloheptane substituted ethers E. R. SQUIBB & SONS, INC. (US) 1987-03-03 US disclosed
US-4608386-A ASTHMA E. R. SQUIBB & SONS, INC. (US) 1986-08-26 US disclosed
US-4575512-A THROMBOXANE SYNTHETASE INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1986-03-11 US disclosed
EP-0163562-A1 7-Oxabicycloheptane substituted ethers E.R. Squibb & Sons, Inc. (US) 1985-12-04 EP disclosed
EP-0161904-A2 Tetrahydrofuranyl and tetrahydrothienyl substituted ethers E.R. Squibb & Sons, Inc. (US) 1985-11-21 EP disclosed
US-4550120-A BRONCHODILATOR AGENTS, ANALGESICS E. R. SQUIBB & SONS, INC. (US) 1985-10-29 US disclosed
US-4542151-A CARDIOVASCULAR, BRONCHODILATION, ANALGESICS, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1985-09-17 US disclosed
US-4521539-A ANALGESICS, CARDIONVASCULAR AND ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1985-06-04 US disclosed