⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24492437 | 0.91 | MMP9 (0.32) | — | |
| SCHEMBL10677092 | 0.78 | — | — | |
| SCHEMBL10675499 | 0.78 | — | — | |
| SCHEMBL11064146 | 0.78 | — | — | |
| SCHEMBL23135540 | 0.78 | — | — | |
| SCHEMBL17207576 | 0.78 | — | — | |
| SCHEMBL24492179 | 0.77 | FFAR2 (0.32) | — | |
| SCHEMBL21676397 | 0.74 | CA12 (0.37) | — | |
| SCHEMBL10686030 | 0.74 | — | — | |
| SCHEMBL15993879 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| US-20230295137-A1 | COVALENT EGFR INHIBITORS AND METHODS OF USE THEREOF | DANA FARBER CANCER INST INC (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230295137-A1 | COVALENT EGFR INHIBITORS AND METHODS OF USE THEREOF | DANA FARBER CANCER INST INC (US) | 2023-09-21 | — | — | US | disclosed |
| WO-2023069959-A1 | COVALENT EGFR INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2022006548-A1 | INHIBITORS OF YAP/TAZ-TEAD ONCOPROTEINS, SYNTHESIS AND USE THEREOF | BRIDGENE BIOSCIENCES, INC. (US) | 2022-01-06 | — | — | WO | disclosed |
| WO-2021026162-A1 | METHOD FOR PROTEOME-WIDE DISCOVERY OF COVALENT LIGANDS AND COMPOSITIONS THEREOF | BRIDGENE BIOSCIENCES, INC. (US) | 2021-02-11 | — | — | WO | disclosed |
| US-4781752-A | Haloacetamidines compositions and the herbicidal use thereof | STAUFFER CHEMICAL COMPANY (US) | 1988-11-01 | — | — | US | disclosed |
| US-4670593-A | Haloacetamidines and the herbicidal use thereof | STAUFFER CHEMICAL CO. (US) | 1987-06-02 | — | — | US | disclosed |