Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677690 | 0.91 | — | — | |
| SCHEMBL24492179 | 0.83 | FFAR2 (0.32) | MMP1 | |
| SCHEMBL22916996 | 0.77 | MMP9 (0.37) | MMP9MMP8CA12CA1CA2 | |
| SCHEMBL25748772 | 0.75 | MMP9 (0.36) | MMP9MMP8CA12CA1CA2 | |
| SCHEMBL23690961 | 0.73 | DPP4 (0.50) | MMP9MMP8CA12CA1CA2 | |
| SCHEMBL24476066 | 0.73 | MMP9 (0.34) | MMP9MMP8CA12CA1CA2 | |
| SCHEMBL21126099 | 0.72 | CA2 (0.37) | MMP9MMP8CA12CA1CA2 | |
| Bromide SCHEMBL11517063 | 0.71 | DPP4 (0.48) | MMP9MMP8CA12CA1CA2 | |
| SCHEMBL10677092 | 0.71 | — | — | |
| SCHEMBL23135540 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117051-A1 | MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 北京鞍石生物科技有限责任公司 | 2022-06-09 | — | — | WO | disclosed |