Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678314 | 1.00 | NOTUM (0.52) | NOTUMALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL10683326 | 0.85 | NOTUM (0.49) | NOTUMALDH1A1KDM4EPKMLMNA | |
| SCHEMBL10686003 | 0.85 | PKM (0.51) | NOTUMALDH1A1KDM4EPKMCYP1A2 | |
| SCHEMBL15187564 | 0.81 | NOTUM (0.65) | NOTUMALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL10683148 | 0.76 | ALDH1A1 (0.67) | NOTUMALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL10683152 | 0.76 | ALDH1A1 (0.67) | NOTUMALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL10681617 | 0.74 | ALDH1A1 (0.46) | NOTUMALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL10682774 | 0.74 | GAA (0.60) | NOTUMALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL10682781 | 0.74 | GAA (0.60) | NOTUMALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL26103579 | 0.72 | ALDH1A1 (0.50) | NOTUMALDH1A1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792609-A | SUNSCREEN AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | claimed |
| EP-0207287-A2 | Indole derivatives, process for their preparation and cosmetic preparation containing them | BAYER AG (DE) | 1987-01-07 | — | — | EP | claimed |
| US-4792609-A | SUNSCREEN AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | disclosed |
| EP-0207287-A2 | Indole derivatives, process for their preparation and cosmetic preparation containing them | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |