Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683148 | 1.00 | ALDH1A1 (0.67) | ALDH1A1NOTUMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10682781 | 0.93 | GAA (0.60) | ALDH1A1NOTUMSMN1; SMN2POLBGAA | |
| SCHEMBL10682774 | 0.93 | GAA (0.60) | ALDH1A1NOTUMSMN1; SMN2POLBGAA | |
| SCHEMBL8904589 | 0.81 | ALDH1A1 (0.65) | ALDH1A1NOTUMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29554766 | 0.80 | NPC1 (0.71) | ALDH1A1NOTUMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2116912 | 0.80 | NPC1 (0.71) | ALDH1A1NOTUMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10678854 | 0.78 | NOTUM (0.61) | ALDH1A1NOTUMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10678314 | 0.76 | NOTUM (0.52) | ALDH1A1NOTUMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10678307 | 0.76 | NOTUM (0.52) | ALDH1A1NOTUMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26695252 | 0.75 | ALDH1A1 (0.49) | ALDH1A1NOTUMNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792609-A | SUNSCREEN AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | disclosed |
| EP-0207287-A2 | Indole derivatives, process for their preparation and cosmetic preparation containing them | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |