Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484906 | 0.83 | RORC (0.53) | RORCLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL11836081 | 0.82 | SMN1; SMN2 (0.53) | RORCLMNATDP1MEN1KMT2A | |
| SCHEMBL25567671 | 0.81 | RORC (0.53) | RORCLMNAMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8139012 | 0.81 | RORC (0.52) | RORCLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL1767942 | 0.80 | RORC (0.52) | RORCLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL12273496 | 0.80 | RORC (0.52) | RORCLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL6279399 | 0.80 | CNR2 (0.58) | RORCCYP1A2MAPTSMN1; SMN2HTT | |
| SCHEMBL7377460 | 0.79 | MMP8 (0.56) | RORCLMNATDP1MEN1KMT2A | |
| SCHEMBL6040918 | 0.79 | CNR2 (0.47) | RORCLMNAKMT2ACYP1A2MAPT | |
| SCHEMBL4115523 | 0.78 | CNR2 (0.53) | RORCLMNAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720506-A | Immunomodulating agent | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0094599-B1 | USE OF AMINOPHENYLACETIC ACID DERIVATIVES FOR THE MANUFACTURE OF AN IMMUNOMODULATING MEDICAL PREPARATION | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-01 | — | — | EP | disclosed |
| EP-0094599-A1 | Use of aminophenylacetic acid derivatives for the manufacture of an immunomodulating medical preparation | MITSUBISHI KASEI CORPORATION (JP) | 1983-11-23 | — | — | EP | disclosed |