SCHEMBL25567671

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10679282	0.81	RORC (0.62)	RORCHTTLMNAMAPTSMN1; SMN2
	SCHEMBL3484906	0.80	RORC (0.53)	RORCLMNAMAPTSMN1; SMN2TSHR
	Hydrochloric Acid SCHEMBL8139012	0.79	RORC (0.52)	RORCLMNAMAPTSMN1; SMN2TSHR
	SCHEMBL25534917	0.79	PDE2A (0.44)	RORCHTTLMNASMN1; SMN2TSHR
	SCHEMBL31323285	0.77	RAB9A (0.71)	CA1CA2RAB9AHTTMAPT
	SCHEMBL10169477	0.75	LMNA (0.49)	RORCRAB9AHTTLMNASMN1; SMN2
	SCHEMBL12273496	0.75	RORC (0.52)	RORCRAB9ALMNAMAPTSMN1; SMN2
	SCHEMBL1767942	0.75	RORC (0.52)	RORCRAB9ALMNAMAPTSMN1; SMN2
	SCHEMBL397134	0.75	CYP1A2 (0.53)	RORCRAB9ALMNAMAPTSMN1; SMN2
	SCHEMBL6279399	0.74	CNR2 (0.58)	RORCRAB9AHTTMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.