Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679390 | 1.00 | LMNA (0.30) | LMNA | |
| SCHEMBL10685435 | 0.90 | LMNA (0.35) | LMNA | |
| SCHEMBL10685449 | 0.90 | LMNA (0.35) | LMNA | |
| SCHEMBL10684677 | 0.86 | — | — | |
| SCHEMBL10684667 | 0.86 | — | — | |
| SCHEMBL10679395 | 0.84 | LMNA (0.40) | LMNA | |
| SCHEMBL10679398 | 0.84 | LMNA (0.40) | LMNA | |
| SCHEMBL11107013 | 0.78 | ALOX15 (0.32) | LMNA | |
| SCHEMBL5452973 | 0.77 | HCAR2 (0.39) | — | |
| SCHEMBL5452972 | 0.77 | HCAR2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761420-A | CARDIOVASCULAR DISORDERS | LABORATOIRES SYNTEX S.A. (FR) | 1988-08-02 | — | — | US | disclosed |
| EP-0249245-A2 | Antihypertensive dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1987-12-16 | — | — | EP | disclosed |