Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 9/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685144 | 0.93 | MTNR1B (0.40) | MTNR1BMTNR1AMAPTLMNATSHR | |
| SCHEMBL10367314 | 0.89 | MTNR1A (0.45) | MTNR1BMTNR1APPARGMAPTSMN1; SMN2 | |
| SCHEMBL10682398 | 0.87 | KDM4E (0.43) | MTNR1BMTNR1APPARGMAPTPPARD | |
| SCHEMBL10682878 | 0.86 | PPARD (0.38) | MTNR1BMTNR1APPARGMAPTPPARD | |
| SCHEMBL10366109 | 0.82 | PPARD (0.34) | MTNR1BMTNR1APPARGMAPTPPARD | |
| SCHEMBL10677550 | 0.82 | KDM4E (0.41) | MTNR1BMTNR1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL10366214 | 0.81 | MTNR1A (0.36) | MTNR1BMTNR1AMAPTTSHR | |
| SCHEMBL10684286 | 0.79 | MTNR1A (0.44) | MTNR1BMTNR1APPARGMAPTSMN1; SMN2 | |
| SCHEMBL10680342 | 0.78 | KDM4E (0.40) | MTNR1BMTNR1APPARGMAPTPPARD | |
| SCHEMBL10368348 | 0.77 | KDM4E (0.41) | MTNR1BMTNR1APPARGMAPTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | claimed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | claimed |