Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 7/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10470573 | 0.80 | CHRNB4 (0.41) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| Oxalic Acid SCHEMBL10471042 | 0.78 | DRD1 (0.33) | CHRNB2CHRNA4HTR2CADRA2C | |
| Oxalic Acid SCHEMBL10677176 | 0.74 | ATM (0.50) | — | |
| Oxalic Acid SCHEMBL10470582 | 0.73 | ATM (0.49) | — | |
| Oxalic Acid SCHEMBL10470580 | 0.73 | ATM (0.49) | — | |
| SCHEMBL28288791 | 0.67 | — | — | |
| SCHEMBL3447095 | 0.66 | HTR2C (0.66) | CHRNB2CHRNA4HTR2CHTR2AHTR2B | |
| SCHEMBL1818896 | 0.65 | SLC9A1 (0.48) | CHRNB2CHRNA4HTR2CCDC25B | |
| SCHEMBL1818895 | 0.65 | SLC9A1 (0.48) | CHRNB2CHRNA4HTR2CCDC25B | |
| SCHEMBL1818893 | 0.65 | SLC9A1 (0.48) | CHRNB2CHRNA4HTR2CCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761413-A | CYTOPROTECTION, ANTISECRETORY AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-08-02 | — | — | US | claimed |