Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515264 | 0.83 | ALDH1A1 (0.64) | ALDH1A1POLBMEN1MAPTKMT2A | |
| SCHEMBL10675251 | 0.83 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1POLBMEN1MAPT | |
| SCHEMBL10677226 | 0.82 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1HSD17B10POLBMEN1 | |
| SCHEMBL16116944 | 0.82 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1HSD17B10POLBMEN1 | |
| SCHEMBL10678708 | 0.81 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1HSD17B10POLBMEN1 | |
| SCHEMBL10675268 | 0.81 | HSD11B1 (0.53) | ALDH1A1HSD17B10KMT2ASMN1; SMN2TP53 | |
| SCHEMBL16526226 | 0.81 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1HSD17B10POLBMEN1 | |
| SCHEMBL10677159 | 0.81 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1HSD17B10POLBMEN1 | |
| SCHEMBL10674018 | 0.80 | GAA (0.59) | ALDH1A1L3MBTL1HSD17B10MEN1KMT2A | |
| SCHEMBL10674370 | 0.80 | HSD11B1 (0.52) | ALDH1A1KMT2ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766120-A | ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| US-4663323-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4540703-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-09-10 | — | — | US | disclosed |