Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13080893 | 0.88 | TSHR (0.40) | HSD17B10ALDH1A1CA1CA2TSHR | |
| SCHEMBL13391772 | 0.85 | ALDH1A1 (0.43) | DGAT1ALDH1A1THRBTSHR | |
| SCHEMBL17574066 | 0.84 | DGAT1 (0.42) | DGAT1HSD17B10ALDH1A1TSHR | |
| SCHEMBL355529 | 0.83 | TSHR (0.38) | DGAT1ALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL2183590 | 0.83 | DGAT1 (0.35) | DGAT1ALDH1A1THRBTSHR | |
| SCHEMBL1691335 | 0.82 | DGAT1 (0.38) | DGAT1ALDH1A1THRBTSHR | |
| SCHEMBL16869153 | 0.81 | DGAT1 (0.34) | DGAT1CA2THRBTSHR | |
| SCHEMBL27265814 | 0.81 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL356764 | 0.81 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL30805232 | 0.79 | CYP4A11 (0.41) | DGAT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775692-A | ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT | TORAY INDUSTRIES, INC. (JP) | 1988-10-04 | — | — | US | disclosed |