Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | HRH2 | P25021 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10666871 | 0.99 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2HTR1ADRD2 | |
| Ammonia Solution, Strong SCHEMBL10669228 | 0.97 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2HTR1ADRD2 | |
| SCHEMBL20972295 | 0.93 | TSHR (0.71) | KDM4EALDH1A1SMN1; SMN2TSHRHRH2 | |
| SCHEMBL17905719 | 0.92 | TSHR (0.65) | KDM4EALDH1A1SMN1; SMN2TSHRHRH2 | |
| SCHEMBL13293711 | 0.88 | ALDH1A1 (0.61) | KDM4EALDH1A1SMN1; SMN2HTR1ADRD2 | |
| Ammonia Solution, Strong SCHEMBL10911900 | 0.86 | DRD2 (0.62) | KDM4EALDH1A1SMN1; SMN2HTR1ADRD2 | |
| SCHEMBL8562745 | 0.85 | HRH2 (0.56) | KDM4EALDH1A1SMN1; SMN2FAAHHRH2 | |
| SCHEMBL10934478 | 0.85 | HRH2 (0.59) | TSHRHRH2HRH3 | |
| SCHEMBL5167259 | 0.85 | HRH2 (0.59) | KDM4EALDH1A1SMN1; SMN2FAAHHRH2 | |
| SCHEMBL13544385 | 0.85 | HRH3 (0.74) | KDM4EALDH1A1SMN1; SMN2TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728655-A | ANTIULCER, H2-ANTAGONISTS | FERRER INTERNACIONAL S.A. (ES) | 1988-03-01 | — | — | US | claimed |