Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PRF1 | P14222 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681474 | 1.00 | RXFP1 (0.46) | RXFP1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL13480642 | 0.91 | NFE2L2 (0.44) | RXFP1KDM4ENFE2L2MAPTCYP3A4 | |
| SCHEMBL14156061 | 0.86 | NFE2L2 (0.48) | HPGDSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL14156064 | 0.84 | NFE2L2 (0.47) | HPGDSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL13267724 | 0.84 | ESRRG (0.41) | RXFP1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL13053089 | 0.83 | APP (0.38) | KDM4ENPC1RAB9ANFE2L2ALDH1A1 | |
| SCHEMBL19005901 | 0.81 | HSD17B1 (0.40) | RXFP1HPGDKDM4ERAB9ANFE2L2 | |
| SCHEMBL13515171 | 0.81 | KMT2A (0.47) | RXFP1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL13480638 | 0.81 | RELA (0.40) | KDM4ENFE2L2MAPTCYP3A4RELA | |
| SCHEMBL13480618 | 0.80 | NFE2L2 (0.50) | KDM4ENFE2L2MAPTCYP3A4RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792567-A | Acaricidal aryl arylthien-2-yl ethenes | FMC CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |