P-Xylene

P-Xylene

SCHEMBL10683034

CCCCO.CO.Cc1ccc(C)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
SMN1; SMN2 Q16637 1/20 0.48
LMNA P02545 3/20 0.46
TSHR P16473 2/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ACHE P22303 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
HTT P42858 1/20 0.41
HPGD P15428 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GAA P10253 1/20 0.38
ALB P02768 1/20 0.37
CYP2C9 P11712 1/20 0.37
GCGR P47871 1/20 0.37
SCN5A Q14524 1/20 0.36
SCN2A Q99250 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL3200566 0.97 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
P-Xylene SCHEMBL11202857 0.92 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
P-Cresol SCHEMBL168366 0.88 ACHE (0.59) ALDH1A1SMN1; SMN2LMNAHSD17B10MEN1
Toluene SCHEMBL10674880 0.88 LMNA (0.50) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
Cetyl Alcohol SCHEMBL28089261 0.87 LMNA (0.65) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
Octanol SCHEMBL8391778 0.87 LMNA (0.65) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
Butyl Alcohol SCHEMBL28379306 0.86 ACHE (0.56) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
Toluene SCHEMBL1158310 0.85 LMNA (0.52) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
Toluene SCHEMBL11558249 0.85 LMNA (0.52) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10
Toluene SCHEMBL10337305 0.83 LMNA (0.50) ALDH1A1SMN1; SMN2LMNATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4788277-A OXIDATIVE COUPLING, CATALYST CONTAINING COPPER, DIAMINE, HALOGEN ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-11-29 US disclosed