Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676597 | 0.95 | PRSS1 (0.53) | ALDH1A1RAB9ANPC1TSHRSMN1; SMN2 | |
| SCHEMBL10387919 | 0.85 | KMT2A (0.54) | ALDH1A1RAB9ANPC1TSHRSMN1; SMN2 | |
| SCHEMBL10681078 | 0.85 | SIRT2 (0.52) | DRD2DRD4DRD3KMT2A | |
| SCHEMBL5174546 | 0.84 | MAOB (0.60) | MEN1KMT2AMAOB | |
| SCHEMBL12881943 | 0.84 | THRB (0.58) | TSHRMEN1KMT2A | |
| SCHEMBL7933067 | 0.81 | SMPD1 (0.57) | TSHRKMT2A | |
| SCHEMBL11397174 | 0.81 | SMPD1 (0.57) | TSHRKMT2A | |
| SCHEMBL10388881 | 0.81 | SMPD1 (0.57) | TSHRKMT2A | |
| SCHEMBL14418361 | 0.81 | CHRNB2 (0.55) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7927176 | 0.81 | SMPD1 (0.57) | TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786755-A | ANTAGONISTS, ENZYME INHIBITORS, MEDIATOR RELEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0206567-A2 | Compounds of formula [1,1'-biphenyl]-2-carboxylic acid, 2'-[[[(substituted)phenyl]-(substituted)amino]carbonyl]-, pharmaceutical compositions comprising the compounds, and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4602023-A | Diphenic acid monoamides | WARNER-LAMBERT COMPANY (US) | 1986-07-22 | — | — | US | disclosed |