SCHEMBL7933067

SCHEMBL7933067

CCCCCCCCCCCCCCCCCCOc1cccc(NC=O)c1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.57
TSHR P16473 1/20 0.55
NR1H4 Q96RI1 3/20 0.54
THRB P10828 2/20 0.52
PLA2G4B P0C869 2/20 0.50
THRA P10827 1/20 0.49
GGPS1 O95749 2/20 0.48
FAAH O00519 1/20 0.48
CYP2D6 P10635 1/20 0.47
KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10388881 1.00 SMPD1 (0.57) SMPD1TSHRNR1H4THRBPLA2G4B
SCHEMBL7927176 1.00 SMPD1 (0.57) SMPD1TSHRNR1H4THRBPLA2G4B
SCHEMBL9797279 1.00 SMPD1 (0.57) SMPD1TSHRNR1H4THRBPLA2G4B
SCHEMBL11397174 1.00 SMPD1 (0.57) SMPD1TSHRNR1H4THRBPLA2G4B
SCHEMBL12881943 0.94 THRB (0.58) SMPD1TSHRNR1H4THRBPLA2G4B
SCHEMBL10387919 0.89 KMT2A (0.54) SMPD1TSHRNR1H4THRBFAAH
SCHEMBL7654175 0.84 PLA2G2A (0.57) SMPD1TSHRTHRBTHRA
SCHEMBL10676597 0.83 PRSS1 (0.53) TSHRTHRBKMT2A
SCHEMBL1187511 0.83 HTT (0.55) NR1H4CYP2D6KMT2A
SCHEMBL10683066 0.81 ALDH1A1 (0.52) TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed