Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14951518 | 0.81 | MAPT (0.44) | KMT2ANPC1RAB9AMEN1PTGS1 | |
| SCHEMBL10683056 | 0.77 | NR1H2 (0.42) | POLBKMT2APTGS1PTGS2GAA | |
| SCHEMBL10674108 | 0.75 | PTGS1 (0.43) | POLBKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9784599 | 0.73 | ALDH1A1 (0.47) | POLBKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9077198 | 0.73 | NPC1 (0.59) | KMT2ANPC1RAB9AMEN1PTGS1 | |
| SCHEMBL14516372 | 0.72 | PTGS1 (0.73) | POLBKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9367490 | 0.70 | POLB (0.65) | POLBKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9834330 | 0.69 | KMT2A (0.61) | POLBKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9370537 | 0.68 | POLB (0.61) | POLBKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL14891358 | 0.67 | PTGS1 (0.48) | POLBKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4723031-A | Processes for synthesizing substituted and unsubstituted aminoacetate esters | CHEVRON RESEARCH COMPANY (US) | 1988-02-02 | — | — | US | disclosed |
| US-4643762-A | Herbicidal 5-amino-3-oxo-4-(3-substituted-phenyl)-4-pyrroline and derivatives thereof | CHEVRON RESEARCH COMPANY (US) | 1987-02-17 | — | — | US | disclosed |