Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17634157 | 0.87 | MTNR1A (0.46) | MTNR1AMEN1KMT2A | |
| SCHEMBL16062271 | 0.85 | MTNR1A (0.51) | MTNR1AMEN1KMT2A | |
| SCHEMBL4138679 | 0.83 | MTNR1A (0.48) | MTNR1AGRIN2B | |
| SCHEMBL12049299 | 0.82 | MEN1 (0.51) | MEN1KMT2APOLBGRIN2BSLC22A1 | |
| SCHEMBL7951734 | 0.82 | MTNR1A (0.55) | MTNR1A | |
| SCHEMBL28765711 | 0.82 | MTNR1A (0.44) | MTNR1AMEN1KMT2A | |
| SCHEMBL19260263 | 0.79 | MTNR1A (0.51) | MTNR1A | |
| SCHEMBL4139663 | 0.79 | MTNR1A (0.60) | MTNR1A | |
| SCHEMBL700861 | 0.79 | MTNR1A (0.56) | MTNR1AGBA1 | |
| SCHEMBL7149457 | 0.79 | MTNR1A (0.56) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |