Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22267930 | 0.93 | ALDH1A1 (0.45) | ALDH1A1TSHRTLR8TLR7TBXAS1 | |
| SCHEMBL28655496 | 0.93 | ALDH1A1 (0.45) | ALDH1A1TSHRTLR8TLR7TBXAS1 | |
| SCHEMBL22762289 | 0.89 | TLR8 (0.49) | ALDH1A1TSHRTLR8TLR7SIGMAR1 | |
| SCHEMBL11440961 | 0.89 | TBXAS1 (0.47) | TLR8TLR7TBXAS1POLBNOS1 | |
| SCHEMBL6114640 | 0.89 | TBXAS1 (0.47) | TLR8TLR7TBXAS1POLBNOS1 | |
| SCHEMBL6114991 | 0.89 | TBXAS1 (0.47) | TLR8TLR7TBXAS1POLBNOS1 | |
| SCHEMBL11438392 | 0.89 | TBXAS1 (0.47) | TLR8TLR7TBXAS1POLBNOS1 | |
| SCHEMBL5691507 | 0.89 | TBXAS1 (0.47) | TLR8TLR7TBXAS1POLBNOS1 | |
| SCHEMBL6114927 | 0.89 | TBXAS1 (0.47) | TLR8TLR7TBXAS1POLBNOS1 | |
| SCHEMBL6114716 | 0.89 | TBXAS1 (0.47) | TLR8TLR7TBXAS1POLBNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269839-A1 | 5-Acylamino-pyrazole derivatives | BAYER AG (DE) | 1988-06-08 | — | — | EP | disclosed |
| EP-0242573-A1 | 5-Acylamino-pyrazole derivatives | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |