Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22762149 | 0.93 | TLR8 (0.43) | TLR8TLR7MITFPOLBMEN1 | |
| SCHEMBL10685285 | 0.89 | ALDH1A1 (0.45) | TLR8TLR7MITFPOLBMEN1 | |
| SCHEMBL22762248 | 0.87 | MITF (0.41) | TLR8TLR7MITFPOLBMEN1 | |
| SCHEMBL22267930 | 0.86 | ALDH1A1 (0.45) | TLR8TLR7MITFPOLBTSHR | |
| SCHEMBL28655496 | 0.86 | ALDH1A1 (0.45) | TLR8TLR7MITFPOLBTSHR | |
| SCHEMBL796651 | 0.84 | — | — | |
| SCHEMBL45207 | 0.82 | TLR8 (0.44) | TLR8TLR7POLBKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6736377 | 0.82 | TLR8 (0.44) | TLR8TLR7POLBKMT2ATSHR | |
| Bromide SCHEMBL556174 | 0.82 | TLR8 (0.44) | TLR8TLR7POLBKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL557786 | 0.82 | TLR8 (0.44) | TLR8TLR7POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247860-A1 | BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-12-10 | — | — | WO | disclosed |