Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | CHKA | P35790 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10502937 | 0.98 | KDM4E (0.67) | KDM4EALDH1A1SIGMAR1MBTD1L3MBTL3 | |
| SCHEMBL10502663 | 0.94 | SIGMAR1 (0.68) | KDM4EALDH1A1SIGMAR1CACNA1GDRD2 | |
| Hydrochloric Acid SCHEMBL10503565 | 0.92 | SIGMAR1 (0.66) | KDM4EALDH1A1SIGMAR1CACNA1GDRD2 | |
| SCHEMBL10665802 | 0.91 | KDM4E (0.62) | KDM4EALDH1A1SIGMAR1MBTD1L3MBTL3 | |
| SCHEMBL10659831 | 0.90 | KDM4E (0.61) | KDM4EALDH1A1SIGMAR1MBTD1L3MBTL3 | |
| SCHEMBL10641996 | 0.90 | KDM4E (0.61) | KDM4EALDH1A1SIGMAR1MBTD1L3MBTL3 | |
| Water SCHEMBL10685378 | 0.89 | SIGMAR1 (0.66) | KDM4EALDH1A1SIGMAR1CACNA1GDRD2 | |
| Water SCHEMBL10685392 | 0.89 | SIGMAR1 (0.66) | KDM4EALDH1A1SIGMAR1CACNA1GDRD2 | |
| SCHEMBL10599132 | 0.89 | KDM4E (0.59) | KDM4EALDH1A1SIGMAR1MBTD1L3MBTL3 | |
| SCHEMBL23851111 | 0.88 | ALDH1A1 (0.87) | KDM4EALDH1A1SIGMAR1MBTD1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725597-A | ANTIALLERGEN, ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM LTD. (US) | 1988-02-16 | — | — | US | claimed |