Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.87 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.69 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.61 |
| ▸ | LSS | P48449 | 1/20 | 0.58 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.57 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.57 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CHKA | P35790 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937990 | 0.95 | ALDH1A1 (0.95) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| SCHEMBL11227514 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL7281619 | 0.93 | ALDH1A1 (0.91) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| SCHEMBL1276590 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| Ammonia Solution, Strong SCHEMBL3813664 | 0.91 | ALDH1A1 (0.96) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| Hydrochloric Acid SCHEMBL7405362 | 0.91 | ALDH1A1 (0.96) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| SCHEMBL10685802 | 0.88 | KDM4E (0.69) | ALDH1A1KDM4EHRH3SIGMAR1LSS | |
| SCHEMBL3041586 | 0.88 | ALDH1A1 (0.69) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| Ammonia Solution, Strong SCHEMBL2924519 | 0.87 | ALDH1A1 (0.81) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| SCHEMBL11610713 | 0.87 | ALDH1A1 (0.88) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883925-A1 | CYCLIC UREAS | Sironax Ltd (KY) | 2021-09-29 | — | — | EP | disclosed |
| CN-102471339-A | Pyrrolopyridine inhibitors of kinases | ABBOTT LAB | 2012-05-23 | — | — | CN | disclosed |