SCHEMBL10686262

SCHEMBL10686262

Fc1ccccc1C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 5/20 0.39
ACHE P22303 1/20 0.36
SLC22A12 Q96S37 2/20 0.35
KCNE1 P15382 1/20 0.35
KCNQ1 P51787 1/20 0.35
NFE2L2 Q16236 1/20 0.35
HSD11B1 P28845 1/20 0.33
KIF11 P52732 1/20 0.33
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK3 Q15120 1/20 0.32
PDK4 Q16654 1/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10602905 0.89 KCNN4 (0.42) KCNN4ACHESLC22A12KCNE1KCNQ1
SCHEMBL13615442 0.85 KCNN4 (0.37) KCNN4ACHESLC22A12KCNE1KCNQ1
SCHEMBL12764916 0.80 ACHE (0.39) KCNN4ACHESLC22A12KCNE1KCNQ1
SCHEMBL5331319 0.80 KCNN4 (0.41) KCNN4ACHESLC22A12KCNE1KCNQ1
SCHEMBL7937247 0.79 KCNN4 (0.39) KCNN4ACHESLC22A12KCNE1KCNQ1
SCHEMBL29466225 0.78 SLC22A12 (0.46) KCNN4ACHESLC22A12HSD11B1KIF11
SCHEMBL169053 0.78 SLC22A12 (0.46) KCNN4ACHESLC22A12HSD11B1KIF11
SCHEMBL30014426 0.77 PDK1 (0.40) KCNN4ACHESLC22A12KCNE1KCNQ1
Ammonia Solution, Strong SCHEMBL2163470 0.76 SLC22A12 (0.44) KCNN4SLC22A12HSD11B1KIF11ALDH1A1
SCHEMBL1600455 0.76 KCNN4 (0.41) KCNN4ACHESLC22A12KCNE1KCNQ1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4743703-A Herbicidal 4-fluoroalkyl-4'-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1988-05-10 US disclosed