SCHEMBL13615442

SCHEMBL13615442

Fc1ccccc1C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 5/20 0.37
SLC22A12 Q96S37 2/20 0.33
ACHE P22303 1/20 0.33
KCNE1 P15382 1/20 0.33
KCNQ1 P51787 1/20 0.33
ELANE P08246 1/20 0.33
NFE2L2 Q16236 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
PTGS2 P35354 1/20 0.31
HSD11B1 P28845 1/20 0.31
KIF11 P52732 1/20 0.31
PDK1 Q15118 1/20 0.31
PDK2 Q15119 1/20 0.31
PDK3 Q15120 1/20 0.31
PDK4 Q16654 1/20 0.31
POLB P06746 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10686262 0.85 KCNN4 (0.39) KCNN4SLC22A12ACHEKCNE1KCNQ1
SCHEMBL28256785 0.85 ELANE (0.36) ELANEALDH1A1HSD11B1KIF11POLB
SCHEMBL10602905 0.85 KCNN4 (0.42) KCNN4SLC22A12ACHEKCNE1KCNQ1
SCHEMBL27309764 0.77 KCNN4 (0.39) KCNN4SLC22A12ACHEKCNE1KCNQ1
SCHEMBL8846995 0.77 MAPT (0.35) ELANEALDH1A1POLBTDP1L3MBTL1
SCHEMBL12764916 0.76 ACHE (0.39) KCNN4SLC22A12ACHEKCNE1KCNQ1
SCHEMBL5331319 0.76 KCNN4 (0.41) KCNN4SLC22A12ACHEKCNE1KCNQ1
SCHEMBL7937247 0.75 KCNN4 (0.39) KCNN4SLC22A12ACHEKCNE1KCNQ1
SCHEMBL28730692 0.75 LMNA (0.39) ELANEALDH1A1POLBTDP1L3MBTL1
SCHEMBL6265278 0.74 ALDH1A1 (0.48) ELANEALDH1A1KDM4EPDK2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed