Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634091 | 0.92 | THRB (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL8551749 | 0.89 | THRB (0.46) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL2321137 | 0.89 | THRB (0.46) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL27407039 | 0.87 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29597270 | 0.84 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL2320055 | 0.83 | THRB (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL9634868 | 0.83 | TSHR (0.52) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL23881987 | 0.82 | THRB (0.43) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10391374 | 0.82 | TSHR (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL57687 | 0.82 | THRB (0.43) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767883-A | PHOTORESISTS; FLEXIBILITY; LOW VISCOSITY, HIGH GLASS TRANSITION TEMPERATURE; CROSSLINKABLE | EASTMAN KODAK COMPANY (US) | 1988-08-30 | — | — | US | disclosed |