Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57687 | 0.93 | THRB (0.43) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10391374 | 0.93 | TSHR (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL57689 | 0.93 | THRB (0.43) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL28390939 | 0.92 | THRB (0.42) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL23881987 | 0.91 | THRB (0.43) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL29597270 | 0.90 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL2321137 | 0.89 | THRB (0.46) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10686304 | 0.89 | THRB (0.48) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL9577905 | 0.88 | TSHR (0.40) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL2163307 | 0.86 | THRB (0.39) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1026505-A | — | — | None | — | — | JP | disclosed |
| EP-0724503-B1 | ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES | MINNESOTA MINING & MFG (US) | 1998-11-11 | — | — | EP | disclosed |
| US-5736747-A | SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5733648-A | FOR AMINOPLASTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| US-5710281-A | Organic compounds suitable as reactive diluents and binder precursor compositions including same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5709935-A | ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5667842-A | Abrasive articles incorporating addition polymerizable resins and reactive diluents, and methods of making said abrasive articles | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5580647-A | OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0724503-A1 | ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |
| US-5523152-A | Organic compounds suitable as reactive diluents, and binder precursor compositions including same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| WO-1995011774-A1 | ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-04 | — | — | WO | disclosed |
| JP-S6426505-A | PHOTO-SETTING COMPOSITION FOR DENTAL MATERIAL | SHOWA DENKO KK | 1989-01-27 | — | — | JP | disclosed |
| EP-0193643-A2 | Curable resin composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1986-09-10 | — | — | EP | disclosed |
| US-4070497-A | Process of applying and curing a plurality of coatings | PPG INDUSTRIES, INC. (US) | 1978-01-24 | — | — | US | disclosed |