Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.44 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130741 | 0.84 | LMNA (0.51) | ALDH1A1LMNAKDM4EMETTL3METTL14 | |
| SCHEMBL10445864 | 0.82 | LMNA (0.66) | ALDH1A1LMNAKDM4ENR4A2TP53 | |
| SCHEMBL30309505 | 0.82 | LMNA (0.66) | ALDH1A1LMNAKDM4ENR4A2TP53 | |
| SCHEMBL6211765 | 0.81 | LMNA (0.42) | ALDH1A1LMNAKDM4ENR4A2MEN1 | |
| SCHEMBL8130462 | 0.80 | LMNA (0.47) | ALDH1A1LMNAKDM4EMETTL3METTL14 | |
| SCHEMBL6214250 | 0.80 | LMNA (0.45) | ALDH1A1LMNAKDM4EMETTL3METTL14 | |
| SCHEMBL30234406 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4ENR4A2TP53 | |
| SCHEMBL30309442 | 0.78 | LMNA (0.53) | ALDH1A1LMNAKDM4ENR4A2MET | |
| SCHEMBL16207451 | 0.78 | LMNA (0.53) | ALDH1A1LMNAKDM4ENR4A2MET | |
| SCHEMBL17883637 | 0.78 | LMNA (0.53) | ALDH1A1LMNAKDM4ENR4A2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251308-A1 | 4-Quinolone-3-carboxylic-acid derivatives, process for their synthesis and pharmaceutical preparations containing them | Chemie Linz Gesellschaft m.b.H. (AT) | 1988-01-07 | — | — | EP | disclosed |