Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686442 | 0.93 | ALDH1A1 (0.50) | ALDH1A1NPSR1MAOACISD1MAPT | |
| SCHEMBL10690203 | 0.86 | ALDH1A1 (0.52) | ALDH1A1NPSR1MAOACISD1MAPT | |
| SCHEMBL10690582 | 0.83 | PPARG (0.48) | ALDH1A1NPSR1MAPTPTPN1MAOB | |
| SCHEMBL10684998 | 0.82 | ALDH1A1 (0.50) | ALDH1A1NPSR1MAOACISD1MAPT | |
| SCHEMBL10690807 | 0.78 | PPARG (0.50) | ALDH1A1NPSR1MAOACISD1MAPT | |
| SCHEMBL10684703 | 0.77 | ALDH1A1 (0.52) | ALDH1A1NPSR1MAOACISD1MAPT | |
| SCHEMBL10686913 | 0.76 | ALDH1A1 (0.56) | ALDH1A1NPSR1MAOACISD1MAPT | |
| SCHEMBL10687947 | 0.74 | ALDH1A1 (0.54) | ALDH1A1NPSR1MAOACISD1MAPT | |
| SCHEMBL10688836 | 0.74 | ALDH1A1 (0.51) | ALDH1A1NPSR1MAOACISD1MAPT | |
| SCHEMBL10686384 | 0.73 | PPARG (0.52) | ALDH1A1NPSR1MAOACISD1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |